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Atorvastatin Prevents Myocardial Fibrosis in Spontaneous Hypertension via Interleukin-6 (IL-6)/Signal Transducer and Activator of Transcription 3 (STAT3)/Endothelin-1 (ET-1) Pathway

BACKGROUND: Hypertension is a leading global disease, and myocardial fibrosis is an important adverse effect of hypertension, seriously threatening human health. The IL-6/STAT3 pathway and endothelin-1 (ET-1) were previously suggested to play a part in myocardial fibrosis. MATERIAL/METHODS: To inves...

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Detalles Bibliográficos
Autores principales: Fang, Tianfu, Guo, Baoliang, Xue, Lujing, Wang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338014/
https://www.ncbi.nlm.nih.gov/pubmed/30631031
http://dx.doi.org/10.12659/MSM.912032