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Smaller Body Size, Early Postnatal Lethality, and Cortical Extracellular Matrix-Related Gene Expression Changes of Cyfip2-Null Embryonic Mice

Cytoplasmic FMR1-interacting protein 2 (CYFIP2) is a key component of the WAVE regulatory complex (WRC) which regulates actin polymerization and branching in diverse cellular compartments. Recent whole exome sequencing studies identified de novo hotspot variants in CYFIP2 from patients with early-on...

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Detalles Bibliográficos
Autores principales: Zhang, Yinhua, Kang, Hyojin, Lee, Yeunkum, Kim, Yoonhee, Lee, Bokyoung, Kim, Jin Yong, Jin, Chunmei, Kim, Shinhyun, Kim, Hyun, Han, Kihoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338024/
https://www.ncbi.nlm.nih.gov/pubmed/30687000
http://dx.doi.org/10.3389/fnmol.2018.00482