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Smaller Body Size, Early Postnatal Lethality, and Cortical Extracellular Matrix-Related Gene Expression Changes of Cyfip2-Null Embryonic Mice
Cytoplasmic FMR1-interacting protein 2 (CYFIP2) is a key component of the WAVE regulatory complex (WRC) which regulates actin polymerization and branching in diverse cellular compartments. Recent whole exome sequencing studies identified de novo hotspot variants in CYFIP2 from patients with early-on...
Autores principales: | Zhang, Yinhua, Kang, Hyojin, Lee, Yeunkum, Kim, Yoonhee, Lee, Bokyoung, Kim, Jin Yong, Jin, Chunmei, Kim, Shinhyun, Kim, Hyun, Han, Kihoon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338024/ https://www.ncbi.nlm.nih.gov/pubmed/30687000 http://dx.doi.org/10.3389/fnmol.2018.00482 |
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