IRE1α Activation in Bone Marrow-Derived Dendritic Cells Modulates Innate Recognition of Melanoma Cells and Favors CD8(+) T Cell Priming

The IRE1α/XBP1s signaling pathway is an arm of the unfolded protein response (UPR) that safeguards the fidelity of the cellular proteome during endoplasmic reticulum (ER) stress, and that has also emerged as a key regulator of dendritic cell (DC) homeostasis. However, in the context of DC activation...

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Detalles Bibliográficos
Autores principales: Medel, Bernardita, Costoya, Cristobal, Fernandez, Dominique, Pereda, Cristian, Lladser, Alvaro, Sauma, Daniela, Pacheco, Rodrigo, Iwawaki, Takao, Salazar-Onfray, Flavio, Osorio, Fabiola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338037/
https://www.ncbi.nlm.nih.gov/pubmed/30687308
http://dx.doi.org/10.3389/fimmu.2018.03050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338037/
https://www.ncbi.nlm.nih.gov/pubmed/30687308
http://dx.doi.org/10.3389/fimmu.2018.03050

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