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Typing complex meningococcal vaccines to understand diversity and population structure of key vaccine antigens

Background: Protein-conjugate capsular polysaccharide vaccines can potentially control invasive meningococcal disease (IMD) caused by five (A, C, W, X, Y) of the six IMD-associated serogroups.  Concerns raised by immunological similarity of the serogroup B capsule to human neural cell carbohydrates,...

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Detalles Bibliográficos
Autores principales: Rodrigues, Charlene M. C., Chan, Hannah, Vipond, Caroline, Jolley, Keith, Harrison, Odile B., Wheeler, Jun, Whiting, Gail, Feavers, Ian M., Maiden, Martin C. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338130/
https://www.ncbi.nlm.nih.gov/pubmed/30687793
http://dx.doi.org/10.12688/wellcomeopenres.14859.2