A RECK-WNT7 Receptor-Ligand Interaction Enables Isoform-Specific Regulation of Wnt Bioavailability

WNT7A and WNT7B control CNS angiogenesis and blood-brain barrier formation by activating endothelial Wnt/β-catenin signaling. The GPI-anchored protein RECK and adhesion G protein-coupled receptor GPR124 critically regulate WNT7-specific signaling in concert with FZD and LRP co-receptors. Here, we de...

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Detalles Bibliográficos
Autores principales: Vallon, Mario, Yuki, Kanako, Nguyen, Thi D., Chang, Junlei, Yuan, Jenny, Siepe, Dirk, Miao, Yi, Essler, Markus, Noda, Makoto, Garcia, K. Christopher, Kuo, Calvin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338448/
https://www.ncbi.nlm.nih.gov/pubmed/30304675
http://dx.doi.org/10.1016/j.celrep.2018.09.045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338448/
https://www.ncbi.nlm.nih.gov/pubmed/30304675
http://dx.doi.org/10.1016/j.celrep.2018.09.045

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