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Opening up about Tissue Transglutaminase: When Conformation Matters More than Enzymatic Activity

Tissue transglutaminase (tTG), also referred to as type 2 transglutaminase or Gα(h), can bind and hydrolyze GTP, as well as function as a protein crosslinking enzyme. tTG is widely expressed and can be detected both inside cells and in the extracellular space. In contrast to many enzymes, the active...

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Detalles Bibliográficos
Autores principales: Katt, William P., Antonyak, Marc A., Cerione, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338449/
https://www.ncbi.nlm.nih.gov/pubmed/30662957
http://dx.doi.org/10.20900/mo.20180011