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Cellular cartography of the organ of Corti based on optical tissue clearing and machine learning
The highly organized spatial arrangement of sensory hair cells in the organ of Corti is essential for inner ear function. Here, we report a new analytical pipeline, based on optical clearing of tissue, for the construction of a single-cell resolution map of the organ of Corti. A sorbitol-based optic...
Autores principales: | Urata, Shinji, Iida, Tadatsune, Yamamoto, Masamichi, Mizushima, Yu, Fujimoto, Chisato, Matsumoto, Yu, Yamasoba, Tatsuya, Okabe, Shigeo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338463/ https://www.ncbi.nlm.nih.gov/pubmed/30657453 http://dx.doi.org/10.7554/eLife.40946 |
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