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Overexpression of miR-489 derails mammary hierarchy structure and inhibits HER2/neu-induced tumorigenesis

Although it has been demonstrated that transformed progenitor cell population can contribute to tumor initiation, factors contributing to this malignant transformation are poorly known. Using in vitro and xenograft based models, previous studies demonstrated that miR-489 acts as a tumor suppressor m...

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Detalles Bibliográficos
Autores principales: Patel, Y, Soni, M, Awagulerwitsch, A, Kern, MJ, Liu, S, Shah, N, Singh, UP, Chen, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338493/
https://www.ncbi.nlm.nih.gov/pubmed/30104710
http://dx.doi.org/10.1038/s41388-018-0439-1