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Galactose-Deficient IgA1-Specific Antibody Recognizes GalNAc-Modified Unique Epitope on Hinge Region of IgA1

Galactose-deficient IgA1 (Gd-IgA1) that exposes GalNAc or sialylated GalNAc has been shown to be associated with disease activity of IgA nephropathy (IgAN). In a previous report, we established an enzyme-linked immunosorbent assay that measures human Gd-IgA1 using a specific monoclonal antibody KM55...

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Detalles Bibliográficos
Autores principales: Yamasaki, Kohei, Suzuki, Hitoshi, Yasutake, Junichi, Yamazaki, Yuji, Suzuki, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338562/
https://www.ncbi.nlm.nih.gov/pubmed/30570353
http://dx.doi.org/10.1089/mab.2018.0041