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STIM2 interacts with AMPK and regulates calcium-induced AMPK activation

AMPK is a crucial regulator of energy homeostasis that acts downstream of its upstream kinase liver kinase B1 (LKB1) and calcium/calmodulin-dependent protein kinase 2 (CaMKK2). LKB1 primarily phosphorylates AMPK after energy stress, whereas calcium-mediated activation of AMPK requires CaMKK2, althou...

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Detalles Bibliográficos
Autores principales: Chauhan, Anoop Singh, Liu, Xiaoguang, Jing, Ji, Lee, Hyemin, Yadav, Raj Kumar, Liu, Jindou, Zhou, Yubin, Gan, Boyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338636/
https://www.ncbi.nlm.nih.gov/pubmed/30335546
http://dx.doi.org/10.1096/fj.201801225R