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Antibiotic collateral sensitivity is contingent on the repeatability of evolution

Antibiotic resistance represents a growing health crisis that necessitates the immediate discovery of novel treatment strategies. One such strategy is the identification of collateral sensitivities, wherein evolution under a first drug induces susceptibility to a second. Here, we report that sequent...

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Detalles Bibliográficos
Autores principales: Nichol, Daniel, Rutter, Joseph, Bryant, Christopher, Hujer, Andrea M., Lek, Sai, Adams, Mark D., Jeavons, Peter, Anderson, Alexander R. A., Bonomo, Robert A., Scott, Jacob G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338734/
https://www.ncbi.nlm.nih.gov/pubmed/30659188
http://dx.doi.org/10.1038/s41467-018-08098-6