Gene activated adipose tissue fragments as advanced autologous biomaterials for bone regeneration: osteogenic differentiation within the tissue and implications for clinical translation

Cost-effective, expedited approaches for bone regeneration are urgently needed in an ageing population. Bone Morphogenetic Proteins (BMPs) stimulate osteogenesis but their efficacy is impeded by their short half-life. Delivery by genetically modified cells can overcome this problem. However, cell is...

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Detalles Bibliográficos
Autores principales: Ren, Bin, Betz, Volker M., Thirion, Christian, Salomon, Michael, Klar, Roland M., Jansson, Volkmar, Müller, Peter E., Betz, Oliver B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338750/
https://www.ncbi.nlm.nih.gov/pubmed/30659209
http://dx.doi.org/10.1038/s41598-018-36283-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338750/
https://www.ncbi.nlm.nih.gov/pubmed/30659209
http://dx.doi.org/10.1038/s41598-018-36283-6

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