Lsd1 as a therapeutic target in Gfi1-activated medulloblastoma

Drugs that modify the epigenome are powerful tools for treating cancer, but these drugs often have pleiotropic effects, and identifying patients who will benefit from them remains a major clinical challenge. Here we show that medulloblastomas driven by the transcription factor Gfi1 are exquisitely d...

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Detalles Bibliográficos
Autores principales: Lee, Catherine, Rudneva, Vasilisa A., Erkek, Serap, Zapatka, Marc, Chau, Lianne Q., Tacheva-Grigorova, Silvia K., Garancher, Alexandra, Rusert, Jessica M., Aksoy, Ozlem, Lea, Robin, Mohammad, Helai P., Wang, Jianxun, Weiss, William A., Grimes, H. Leighton, Pfister, Stefan M., Northcott, Paul A., Wechsler-Reya, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338772/
https://www.ncbi.nlm.nih.gov/pubmed/30659187
http://dx.doi.org/10.1038/s41467-018-08269-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338772/
https://www.ncbi.nlm.nih.gov/pubmed/30659187
http://dx.doi.org/10.1038/s41467-018-08269-5

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