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Syntheses and cytotoxicity of phosphatidylcholines containing ibuprofen or naproxen moieties

In this study, novel phosphatidylcholines containing ibuprofen or naproxen moieties were synthesized in good yields and high purities. Under the given synthesis conditions, the attached drug moieties racemized, which resulted in the formation of phospholipid diastereomers. The comperative studies of...

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Detalles Bibliográficos
Autores principales: Kłobucki, Marek, Urbaniak, Anna, Grudniewska, Aleksandra, Kocbach, Bartłomiej, Maciejewska, Gabriela, Kiełbowicz, Grzegorz, Ugorski, Maciej, Wawrzeńczyk, Czesław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338774/
https://www.ncbi.nlm.nih.gov/pubmed/30659229
http://dx.doi.org/10.1038/s41598-018-36571-1