Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors

Context-dependent inhibition of N-methyl-D-aspartate (NMDA) receptors has important therapeutic implications for the treatment of neurological diseases that are associated with altered neuronal firing and signaling. This is especially true in stroke, where the proton concentration in the afflicted a...

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Detalles Bibliográficos
Autores principales: Regan, Michael C., Zhu, Zongjian, Yuan, Hongjie, Myers, Scott J., Menaldino, Dave S., Tahirovic, Yesim A., Liotta, Dennis C., Traynelis, Stephen F., Furukawa, Hiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338780/
https://www.ncbi.nlm.nih.gov/pubmed/30659174
http://dx.doi.org/10.1038/s41467-019-08291-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338780/
https://www.ncbi.nlm.nih.gov/pubmed/30659174
http://dx.doi.org/10.1038/s41467-019-08291-1

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