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Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors
Context-dependent inhibition of N-methyl-D-aspartate (NMDA) receptors has important therapeutic implications for the treatment of neurological diseases that are associated with altered neuronal firing and signaling. This is especially true in stroke, where the proton concentration in the afflicted a...
Autores principales: | Regan, Michael C., Zhu, Zongjian, Yuan, Hongjie, Myers, Scott J., Menaldino, Dave S., Tahirovic, Yesim A., Liotta, Dennis C., Traynelis, Stephen F., Furukawa, Hiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338780/ https://www.ncbi.nlm.nih.gov/pubmed/30659174 http://dx.doi.org/10.1038/s41467-019-08291-1 |
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