LEADeR role of miR-205 host gene as long noncoding RNA in prostate basal cell differentiation

Though miR-205 function has been largely characterized, the nature of its host gene, MIR205HG, is still completely unknown. Here, we show that only lowly expressed alternatively spliced MIR205HG transcripts act as de facto pri-miRNAs, through a process that involves Drosha to prevent unfavorable spl...

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Detalles Bibliográficos
Autores principales: Profumo, Valentina, Forte, Barbara, Percio, Stefano, Rotundo, Federica, Doldi, Valentina, Ferrari, Elena, Fenderico, Nicola, Dugo, Matteo, Romagnoli, Dario, Benelli, Matteo, Valdagni, Riccardo, Dolfini, Diletta, Zaffaroni, Nadia, Gandellini, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338800/
https://www.ncbi.nlm.nih.gov/pubmed/30659180
http://dx.doi.org/10.1038/s41467-018-08153-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338800/
https://www.ncbi.nlm.nih.gov/pubmed/30659180
http://dx.doi.org/10.1038/s41467-018-08153-2

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