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Characterization of APOBEC3 variation in a population of HIV-1 infected individuals in northern South Africa

BACKGROUND: The apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3 (APOBEC3) genes A3D, A3F, A3G and A3H have all been implicated in the restriction of human immunodeficiency virus type 1 (HIV-1) replication. Polymorphisms in these genes are likely to impact viral replication and fit...

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Detalles Bibliográficos
Autores principales: Matume, Nontokozo D., Tebit, Denis M., Gray, Laurie R., Turner, Stephen D., Rekosh, David, Bessong, Pascal O., Hammarskjöld, Marie-Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339282/
https://www.ncbi.nlm.nih.gov/pubmed/30660178
http://dx.doi.org/10.1186/s12881-018-0740-4