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Characterization of APOBEC3 variation in a population of HIV-1 infected individuals in northern South Africa
BACKGROUND: The apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3 (APOBEC3) genes A3D, A3F, A3G and A3H have all been implicated in the restriction of human immunodeficiency virus type 1 (HIV-1) replication. Polymorphisms in these genes are likely to impact viral replication and fit...
Autores principales: | Matume, Nontokozo D., Tebit, Denis M., Gray, Laurie R., Turner, Stephen D., Rekosh, David, Bessong, Pascal O., Hammarskjöld, Marie-Louise |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339282/ https://www.ncbi.nlm.nih.gov/pubmed/30660178 http://dx.doi.org/10.1186/s12881-018-0740-4 |
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