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Obesity impacts the regulation of miR-10b and its targets in primary breast tumors

BACKGROUND: Obesity increases breast cancer (BC) risk in post-menopausal women by mostly unknown molecular mechanisms which may partly be regulated by microRNAs (miRNAs). METHODS: We isolated RNA from paired benign and malignant biopsies from 83 BC patients and determined miRNA profiles in samples f...

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Detalles Bibliográficos
Autores principales: Meerson, Ari, Eliraz, Yaniv, Yehuda, Hila, Knight, Bridget, Crundwell, Malcolm, Ferguson, Douglas, Lee, Benjamin P., Harries, Lorna W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339293/
https://www.ncbi.nlm.nih.gov/pubmed/30658617
http://dx.doi.org/10.1186/s12885-019-5300-6