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Recombinant O-mannosylated protein production (PstS-1) from Mycobacterium tuberculosis in Pichia pastoris (Komagataella phaffii) as a tool to study tuberculosis infection

BACKGROUND: Pichia pastoris (syn. Komagataella phaffii) is one of the most highly utilized eukaryotic expression systems for the production of heterologous glycoproteins, being able to perform both N- and O-mannosylation. In this study, we present the expression in P. pastoris of an O-mannosylated r...

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Detalles Bibliográficos
Autores principales: Bando-Campos, Giroshi, Juárez-López, Daniel, Román-González, Sergio A., Castillo-Rodal, Antonia I., Olvera, Clarita, López-Vidal, Yolanda, Arreguín-Espinosa, Roberto, Espitia, Clara, Trujillo-Roldán, Mauricio A., Valdez-Cruz, Norma A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339365/
https://www.ncbi.nlm.nih.gov/pubmed/30660186
http://dx.doi.org/10.1186/s12934-019-1059-3