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Reciprocal regulation of integrin β4 and KLF4 promotes gliomagenesis through maintaining cancer stem cell traits

BACKGROUND: The dismal prognosis of patients with glioma is largely attributed to cancer stem cells that display pivotal roles in tumour initiation, progression, metastasis, resistance to therapy, and relapse. Therefore, understanding how these populations of cells maintain their stem-like propertie...

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Detalles Bibliográficos
Autores principales: Ma, Binbin, Zhang, Li, Zou, Yujie, He, Ruiping, Wu, Qiong, Han, Chuanchun, Zhang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339386/
https://www.ncbi.nlm.nih.gov/pubmed/30658712
http://dx.doi.org/10.1186/s13046-019-1034-1