Manipulation of the Alternative NF‐κB Pathway in Mice Has Sexually Dimorphic Effects on Bone

Alternative NF‐κB signaling promotes osteoclastogenesis and pathological bone loss, but the effect of sex on phenotype has not been explored. We disrupted alternative NF‐κB signaling by deletion of upstream kinase NF‐κB‐inducing kinase (NIK) or NF‐κB subunit RelB and found that both NIK‐deficient an...

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Detalles Bibliográficos
Autores principales: Zarei, Allahdad, Yang, Chang, Gibbs, Jesse, Davis, Jennifer L, Ballard, Anna, Zeng, Rong, Cox, Linda, Veis, Deborah J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339559/
https://www.ncbi.nlm.nih.gov/pubmed/30680359
http://dx.doi.org/10.1002/jbm4.10066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339559/
https://www.ncbi.nlm.nih.gov/pubmed/30680359
http://dx.doi.org/10.1002/jbm4.10066

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