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Non-canonical CTD-kinases regulate RNA polymerase II in a gene-class specific manner

Phosphorylation of the carboxyl-terminal domain (CTD) of the largest subunit of RNA polymerase II (Pol II) governs stage-specific interactions with different cellular machines. The CTD consists of Y(1)S(2)P(3)T(4)S(5)P(6)S(7) heptad repeats, and sequential phosphorylations of Ser7, Ser5 and Ser2 occ...

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Detalles Bibliográficos
Autores principales: Nemec, Corey M., Singh, Amit K., Ali, Asfa, Tseng, Sandra C., Syal, Kirtimaan, Ringelberg, Kennedy J., Ho, Yi-Hsuan, Hintermair, Corinna, Ahmad, Mohammad Faiz, Kar, Rajesh Kumar, Gasch, Audrey P., Akhtar, Md. Sohail, Eick, Dirk, Ansari, Aseem Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339578/
https://www.ncbi.nlm.nih.gov/pubmed/30598543
http://dx.doi.org/10.1038/s41589-018-0194-1