Quantification of Lappaconitine in Mouse Blood by UPLC-MS/MS and Its Application to a Pharmacokinetic Study

Lappaconitine is extracted from Aconitum sinomontanum Nakai, which belongs to the Ranunculaceae. Lappaconitine is as a diterpenoid alkaloid used as a nonaddictive analgesic. To assure the rational use of the drug, ultrahigh-pressure liquid chromatography tandem mass spectrometry (UPLC-MS/MS) was con...

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Detalles Bibliográficos
Autores principales: Chen, Fan, Shen, Xiuwei, Huang, Peng, Fu, Huiyan, Jin, Yue, Wen, Congcong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339746/
https://www.ncbi.nlm.nih.gov/pubmed/30723741
http://dx.doi.org/10.1155/2019/6262105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339746/
https://www.ncbi.nlm.nih.gov/pubmed/30723741
http://dx.doi.org/10.1155/2019/6262105

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