Cargando…

Quantification of Lappaconitine in Mouse Blood by UPLC-MS/MS and Its Application to a Pharmacokinetic Study

Lappaconitine is extracted from Aconitum sinomontanum Nakai, which belongs to the Ranunculaceae. Lappaconitine is as a diterpenoid alkaloid used as a nonaddictive analgesic. To assure the rational use of the drug, ultrahigh-pressure liquid chromatography tandem mass spectrometry (UPLC-MS/MS) was con...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Fan, Shen, Xiuwei, Huang, Peng, Fu, Huiyan, Jin, Yue, Wen, Congcong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339746/ https://www.ncbi.nlm.nih.gov/pubmed/30723741 http://dx.doi.org/10.1155/2019/6262105

Ejemplares similares

Pharmacokinetics and UPLC-MS/MS of Delsoline in Mouse Whole Blood
por: Shao, Lingjiu, et al.
Publicado: (2018)

Toxicokinetics of 11 Gelsemium Alkaloids in Rats by UPLC-MS/MS
por: Shen, Xiuwei, et al.
Publicado: (2020)

Determination of Tenacissoside G, Tenacissoside H, and Tenacissoside I in Rat Plasma by UPLC-MS/MS and Their Pharmacokinetics
por: Chen, Fan, et al.
Publicado: (2023)

Development of a robust UPLC-MS/MS method for the quantification of riluzole in human plasma and its application in pharmacokinetics
por: Sun, Zhuo, et al.
Publicado: (2023)

Pharmacokinetics and metabolism of icaritin in rats by UPLC‐MS/MS
por: Huang, Zhen‐Wu, et al.
Publicado: (2019)

Validated UPLC-MS/MS method for quantification of fruquintinib in rat plasma and its application to pharmacokinetic study
por: Mei, Yi-Bin, et al.
Publicado: (2019)

Pharmacokinetic and Metabolism Studies of Curculigoside C by UPLC-MS/MS and UPLC-QTOF-MS
por: Wu, Di, et al.
Publicado: (2018)

Simultaneous Determination of Six Uncaria Alkaloids in Mouse Blood by UPLC–MS/MS and Its Application in Pharmacokinetics and Bioavailability
por: Chen, Lianguo, et al.
Publicado: (2020)

Comparative Pharmacokinetics of Cinobufacini Capsule and Injection by UPLC-MS/MS
por: Li, Ming, et al.
Publicado: (2022)

UPLC–MS/MS assay for quantification of an inhibitor of kinases (Foretinib) in plasma: Application to a pharmacokinetic study in rats
por: Ezzeldin, Essam, et al.
Publicado: (2020)

Development of a UPLC-MS/MS Method for the Quantification of VS-5584 and Its Application in Pharmacokinetic Studies in Rats
por: Zhou, Chunling, et al.
Publicado: (2020)

Development and validation of an UPLC-ESI-MS/MS method for quantification of duvelisib in plasma: application to pharmacokinetic study in rats
por: Darwish, Ibrahim A., et al.
Publicado: (2023)

Development of UPLC-MS/MS Method for Studying the Pharmacokinetic Interaction Between Dasatinib and Posaconazole in Rats
por: Yang, Suili, et al.
Publicado: (2021)

Determination of Gypenoside A and Gypenoside XLIX in Rat Plasma by UPLC-MS/MS and Applied to the Pharmacokinetics and Bioavailability
por: He, Yan, et al.
Publicado: (2022)

Validated UPLC-MS/MS method for the quantification of dasatinib in plasma: Application to pharmacokinetic interaction studies with nutraceuticals in Wistar rats
por: Maher, Hadir M., et al.
Publicado: (2018)

Pharmacokinetics of Dibutyl Phthalate (DBP) in the Rat Determined by UPLC-MS/MS
por: Chang, Li-Wen, et al.
Publicado: (2013)

Pharmacokinetic and Metabolism Studies of 12-Riboside-Pseudoginsengenin DQ by UPLC-MS/MS and UPLC-QTOF-MS(E)
por: Wang, Zhenzhou, et al.
Publicado: (2018)

Development and Validation a UPLC-MS/MS Method for Quantification of Pentoxifylline in Beagle Plasma: Application for Pharmacokinetic Study of Food Effect
por: Xu, Yuxiang, et al.
Publicado: (2023)

Simultaneous Quantification of Four Phenylethanoid Glycosides in Rat Plasma by UPLC-MS/MS and Its Application to a Pharmacokinetic Study of Acanthus Ilicifolius Herb
por: Zhang, Mengqi, et al.
Publicado: (2019)

Determination of Tropifexor in Beagle Dog Plasma by UPLC-MS/MS and Its Application in Pharmacokinetics
por: Su, Yan-Ding, et al.
Publicado: (2022)

Effects of Dexmedetomidine on the Pharmacokinetics of Parecoxib and Its Metabolite Valdecoxib in Beagles by UPLC-MS/MS
por: Hu, Jie, et al.
Publicado: (2020)

Quantification of Zonisamide in Dried Blood Spots and Dried Plasma Spots by UPLC–MS/MS: Application to Clinical Practice
por: Rmandić, Milena, et al.
Publicado: (2022)

The Effect of Posaconazole and Isavuconazole on the Pharmacokinetics of Erdafitinib in Beagle Dogs by UPLC-MS/MS
por: Ruan, Lan-hong, et al.
Publicado: (2021)

Effects of Xuesaitong on the Pharmacokinetics of Losartan: An In Vivo UPLC-MS/MS Study
por: Ma, Weina, et al.
Publicado: (2019)

Development and validation of an UPLC-MS/MS method for the quantification of ethoxzolamide in plasma and bioequivalent buffers: Applications to absorption, brain distribution, and pharmacokinetic studies
por: Gao, Song, et al.
Publicado: (2015)

Simultaneous determination of indapamide, perindopril and perindoprilat in human plasma or whole blood by UPLC-MS/MS and its pharmacokinetic application
por: Tao, Yi, et al.
Publicado: (2018)

Determination of total and unbound docetaxel in plasma by ultrafiltration and UPLC-MS/MS: application to pharmacokinetic studies
por: Sheu, Ming-Thau, et al.
Publicado: (2017)

Determination of parecoxib and valdecoxib in rat plasma by UPLC-MS/MS and its application to pharmacokinetics studies
por: Chen, Mengchun, et al.
Publicado: (2020)

Quantitation of Apremilast in Beagle Dogs Plasma by UPLC-MS-MS and Its Application to Pharmacokinetic Studies
por: Xiong, Wei, et al.
Publicado: (2021)

Development of UPLC-MS/MS method and its pharmacokinetic application for estimation of sertraline in rat plasma
por: Rahman, Mohammad Akhlaquer
Publicado: (2022)

A New UPLC-MS/MS Method Validated for Quantification of Jervine in Rat Plasma and the Study of Its Pharmacokinetics in Rats
por: Chen, Lianguo, et al.
Publicado: (2019)

Genistein Exposure Interferes with Pharmacokinetics of Celecoxib in SD Male Rats by UPLC-MS/MS
por: Zheng, Xiang, et al.
Publicado: (2017)

Pharmacokinetics and Bioavailability Study of Tubeimoside I in ICR Mice by UPLC-MS/MS
por: Chen, Lianguo, et al.
Publicado: (2018)

Pharmacokinetic Analysis of Diosgenin in Rat Plasma by a UPLC-MS/MS Approach
por: Liu, Pei, et al.
Publicado: (2022)

Pharmacokinetics of Herb-Drug Interactions of Plumbagin and Tazemetostat in Rats by UPLC-MS/MS
por: Li, Heng, et al.
Publicado: (2022)

Inhibitory effect of Schisandrin on the pharmacokinetics of poziotinib in vivo and in vitro by UPLC‐MS/MS
por: Wang, Shuanghu, et al.
Publicado: (2023)

Simultaneous Determination of Three Bioactive Constituents from Bletilla striata by UPLC-MS/MS and Application of the Technique to Pharmacokinetic Analyses
por: Chen, Hao, et al.
Publicado: (2019)

Simultaneous Determination of Celecoxib, Dezocine and Dexmedetomidine in Beagle Plasma Using UPLC-MS/MS Method and the Application in Pharmacokinetics
por: Hu, Jie, et al.
Publicado: (2021)

Development of an UPLC-MS/MS Method for the Quantitative Analysis of Upadacitinib in Beagle Dog Plasma and Pharmacokinetics Study
por: Wang, Meng-Jie, et al.
Publicado: (2021)

Development and Validation of UPLC-MS/MS Method for Determination of Enasidenib in Rat Plasma and Its Pharmacokinetic Application
por: Li, Shuang-long, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_6bg0q7pfie55lr7775ur1sg3t1