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Notch3 Targeting: A Novel Weapon against Ovarian Cancer Stem Cells

Notch signaling is frequently activated in ovarian cancer (OC) and contributes to the proliferation and survival of cultured OC cells as well as to tumor formation and angiogenesis in xenograft models. Several studies demonstrate that Notch3 expression renders cancer cells more resistant to carbopla...

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Detalles Bibliográficos
Autores principales: Ceccarelli, Simona, Megiorni, Francesca, Bellavia, Diana, Marchese, Cinzia, Screpanti, Isabella, Checquolo, Saula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339748/
https://www.ncbi.nlm.nih.gov/pubmed/30723507
http://dx.doi.org/10.1155/2019/6264931