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Notch3 Targeting: A Novel Weapon against Ovarian Cancer Stem Cells
Notch signaling is frequently activated in ovarian cancer (OC) and contributes to the proliferation and survival of cultured OC cells as well as to tumor formation and angiogenesis in xenograft models. Several studies demonstrate that Notch3 expression renders cancer cells more resistant to carbopla...
Autores principales: | Ceccarelli, Simona, Megiorni, Francesca, Bellavia, Diana, Marchese, Cinzia, Screpanti, Isabella, Checquolo, Saula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339748/ https://www.ncbi.nlm.nih.gov/pubmed/30723507 http://dx.doi.org/10.1155/2019/6264931 |
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