Longer lifespan in the Rpd3 and Loco signaling results from the reduced catabolism in young age with noncoding RNA

Downregulation of Rpd3 (histone deacetylase) or Loco (regulator of G-protein signaling protein) extends Drosophila lifespan with higher stress resistance. We found rpd3-downregulated long-lived flies genetically interact with loco-upregulated short-lived flies in stress resistance and lifespan. Gene...

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Detalles Bibliográficos
Autores principales: Kopp, Zachary, Park, Yongkyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339784/
https://www.ncbi.nlm.nih.gov/pubmed/30620723
http://dx.doi.org/10.18632/aging.101744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339784/
https://www.ncbi.nlm.nih.gov/pubmed/30620723
http://dx.doi.org/10.18632/aging.101744

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