Premature aging and cancer development in transgenic mice lacking functional CYLD

CYLD is a deubiquitinating enzyme known for its role as a tumor suppressor whose mutation leads to skin appendages tumors and other cancers. In this manuscript we report that the tumor suppressor CYLD, similarly to other renowned tumor suppressor genes, protects from premature aging and cancer. We h...

Descripción completa

Detalles Bibliográficos
Autores principales: Alameda, Josefa P., Ramírez, Ángel, García-Fernández, Rosa A., Navarro, Manuel, Page, Angustias, Segovia, José C., Sanchez, Rebeca, Suárez-Cabrera, Cristian, Paramio, Jesús M., Bravo, Ana, Fernández-Aceñero, M. Jesús, Casanova, M. Llanos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339805/
https://www.ncbi.nlm.nih.gov/pubmed/30631004
http://dx.doi.org/10.18632/aging.101732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339805/
https://www.ncbi.nlm.nih.gov/pubmed/30631004
http://dx.doi.org/10.18632/aging.101732

Ejemplares similares