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HPV-18 E2 protein downregulates antisense noncoding mitochondrial RNA-2, delaying replicative senescence of human keratinocytes

Human and mouse cells display a differential expression pattern of a family of mitochondrial noncoding RNAs (ncmtRNAs), according to proliferative status. Normal proliferating and cancer cells express a sense ncmtRNA (SncmtRNA), which seems to be required for cell proliferation, and two antisense tr...

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Detalles Bibliográficos
Autores principales: Villota, Claudio, Varas-Godoy, Manuel, Jeldes, Emanuel, Campos, América, Villegas, Jaime, Borgna, Vincenzo, Burzio, Luis O., Burzio, Verónica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339806/
https://www.ncbi.nlm.nih.gov/pubmed/30595560
http://dx.doi.org/10.18632/aging.101711