Common CHD8 Genomic Targets Contrast With Model-Specific Transcriptional Impacts of CHD8 Haploinsufficiency

The packaging of DNA into chromatin determines the transcriptional potential of cells and is central to eukaryotic gene regulation. Case sequencing studies have revealed mutations to proteins that regulate chromatin state, known as chromatin remodeling factors, with causal roles in neurodevelopmenta...

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Detalles Bibliográficos
Autores principales: Wade, A. Ayanna, Lim, Kenneth, Catta-Preta, Rinaldo, Nord, Alex S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339895/
https://www.ncbi.nlm.nih.gov/pubmed/30692911
http://dx.doi.org/10.3389/fnmol.2018.00481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339895/
https://www.ncbi.nlm.nih.gov/pubmed/30692911
http://dx.doi.org/10.3389/fnmol.2018.00481

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