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Inhibitory Receptor Crosslinking Quantitatively Dampens Calcium Flux Induced by Activating Receptor Triggering in NK Cells
Natural killer (NK) cell function is regulated by a balance between activating and inhibitory receptors, but the details of this receptor interplay are not extensively understood. We developed a flow cytometry-based assay system in which Ca(2+) flux downstream of antibody-mediated activating recepto...
Autores principales: | Ganesan, Sridharan, Höglund, Petter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339929/ https://www.ncbi.nlm.nih.gov/pubmed/30693005 http://dx.doi.org/10.3389/fimmu.2018.03173 |
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