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Blockade of Store-Operated Calcium Entry Reduces IL-17/TNF Cytokine-Induced Inflammatory Response in Human Myoblasts

Muscle inflammation as in idiopathic inflammatory myopathies (IIM) leads to muscle weakness, mononuclear cell infiltration, and myofiber dysfunction affecting calcium channels. The effects of interleukin-17A (IL-17) and tumor necrosis factor-α (TNFα) on inflammation and calcium changes were investig...

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Detalles Bibliográficos
Autores principales: Beringer, Audrey, Gouriou, Yves, Lavocat, Fabien, Ovize, Michel, Miossec, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339936/
https://www.ncbi.nlm.nih.gov/pubmed/30693003
http://dx.doi.org/10.3389/fimmu.2018.03170