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Noradrenergic stabilization of heterosynaptic LTP requires activation of Epac in the hippocampus

Beta-adrenergic receptor (β-AR) activation by norepinephrine (NE) enhances memory and stabilizes long-term potentiation (LTP), a form of synaptic plasticity believed to underlie some forms of hippocampal memory. LTP can occur at multiple synaptic pathways as a result of strong stimulation to one pat...

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Detalles Bibliográficos
Autores principales: Brandwein, Nathan J., Nguyen, Peter V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340117/
https://www.ncbi.nlm.nih.gov/pubmed/30651375
http://dx.doi.org/10.1101/lm.048660.118