Two functionally redundant sources of retinoic acid secure spermatogonia differentiation in the seminiferous epithelium

In mammals, all-trans retinoic acid (ATRA) is instrumental to spermatogenesis. It is synthesized by two retinaldehyde dehydrogenases (RALDH) present in both Sertoli cells (SCs) and germ cells (GCs). In order to determine the relative contributions of each source of ATRA, we have generated mice lacki...

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Detalles Bibliográficos
Autores principales: Teletin, Marius, Vernet, Nadège, Yu, Jianshi, Klopfenstein, Muriel, Jones, Jace W., Féret, Betty, Kane, Maureen A., Ghyselinck, Norbert B., Mark, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340151/
https://www.ncbi.nlm.nih.gov/pubmed/30487180
http://dx.doi.org/10.1242/dev.170225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340151/
https://www.ncbi.nlm.nih.gov/pubmed/30487180
http://dx.doi.org/10.1242/dev.170225

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