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Genetic and epigenetic determinants establish a continuum of Hsf1 occupancy and activity across the yeast genome
Heat shock factor 1 is the master transcriptional regulator of molecular chaperones and binds to the same cis-acting heat shock element (HSE) across the eukaryotic lineage. In budding yeast, Hsf1 drives the transcription of ∼20 genes essential to maintain proteostasis under basal conditions, yet its...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340206/ https://www.ncbi.nlm.nih.gov/pubmed/30332327 http://dx.doi.org/10.1091/mbc.E18-06-0353 |