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Inducible IFN-γ Expression for MHC-I Upregulation in Devil Facial Tumor Cells

The Tasmanian devil facial tumor (DFT) disease has led to an 80% reduction in the wild Tasmanian devil (Sarcophilus harrisii) population since 1996. The limited genetic diversity of wild devils and the lack of MHC-I expression on DFT cells have been implicated in the lack of immunity against the ori...

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Detalles Bibliográficos
Autores principales: Ong, Chrissie E. B., Lyons, Alan Bruce, Woods, Gregory M., Flies, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340284/
https://www.ncbi.nlm.nih.gov/pubmed/30692995
http://dx.doi.org/10.3389/fimmu.2018.03117