Production of Glycopeptide Derivatives for Exploring Substrate Specificity of Human OGA Toward Sugar Moiety

O-GlcNAcase (OGA) is the only enzyme responsible for removing N-acetyl glucosamine (GlcNAc) attached to serine and threonine residues on proteins. This enzyme plays a key role in O-GlcNAc metabolism. However, the structural features of the sugar moiety recognized by human OGA (hOGA) remain unclear....

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Detalles Bibliográficos
Autores principales: Li, Shanshan, Wang, Jiajia, Zang, Lanlan, Zhu, Hailiang, Guo, Jianshuang, Zhang, Jiabin, Wen, Liuqing, Chen, Yi, Li, Yanhong, Chen, Xi, Wang, Peng George, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340312/
https://www.ncbi.nlm.nih.gov/pubmed/30693278
http://dx.doi.org/10.3389/fchem.2018.00646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340312/
https://www.ncbi.nlm.nih.gov/pubmed/30693278
http://dx.doi.org/10.3389/fchem.2018.00646

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