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Antidepressive Effects of Taraxacum Officinale in a Mouse Model of Depression Are Due to Inhibition of Corticosterone Levels and Modulation of Mitogen-Activated Protein Kinase Phosphatase-1 (Mkp-1) and Brain-Derived Neurotrophic Factor (Bdnf) Expression

BACKGROUND: Depression is a common disorder linked with high levels of chronicity, psycho-social and physical problems, and suicide. Here, we assessed the antidepressant effects of the hydromethanolic extract of Taraxacum officinale and investigated the underlying mechanism. MATERIAL/METHODS: Antide...

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Detalles Bibliográficos
Autores principales: Gao, Cunyou, Kong, Suli, Guo, Benyu, Liang, Xuejun, Duan, Huifeng, Li, Donghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340315/
https://www.ncbi.nlm.nih.gov/pubmed/30636257
http://dx.doi.org/10.12659/MSM.912922