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Antidepressive Effects of Taraxacum Officinale in a Mouse Model of Depression Are Due to Inhibition of Corticosterone Levels and Modulation of Mitogen-Activated Protein Kinase Phosphatase-1 (Mkp-1) and Brain-Derived Neurotrophic Factor (Bdnf) Expression
BACKGROUND: Depression is a common disorder linked with high levels of chronicity, psycho-social and physical problems, and suicide. Here, we assessed the antidepressant effects of the hydromethanolic extract of Taraxacum officinale and investigated the underlying mechanism. MATERIAL/METHODS: Antide...
Autores principales: | Gao, Cunyou, Kong, Suli, Guo, Benyu, Liang, Xuejun, Duan, Huifeng, Li, Donghe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340315/ https://www.ncbi.nlm.nih.gov/pubmed/30636257 http://dx.doi.org/10.12659/MSM.912922 |
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