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Mouse model of anti-NMDA receptor post–herpes simplex encephalitis

OBJECTIVE: To develop an endogenous rodent model of postinfectious anti-NMDA receptor (NMDAR) encephalitis. METHODS: Six mice were inoculated intranasally with herpes simplex virus (HSV) 1 and subsequently treated with acyclovir for 2 weeks. Serum was collected at 3, 6, and 8 weeks postinoculation a...

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Detalles Bibliográficos
Autores principales: Linnoila, Jenny, Pulli, Benjamin, Armangué, Thaís, Planagumà, Jesús, Narsimhan, Radha, Schob, Stefan, Zeller, Matthias W.G., Dalmau, Josep, Chen, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340334/
https://www.ncbi.nlm.nih.gov/pubmed/30697582
http://dx.doi.org/10.1212/NXI.0000000000000529