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Precision medicine approaches for the management of Ewing sarcoma: current perspectives

Advancements in molecular and genetic techniques have significantly furthered our biological understanding of Ewing sarcoma (ES). ES is typified by a driving TET–ETS fusion with an otherwise relatively quiet genome. Detection of one of several characteristic fusions, most commonly EWSR1–FLI1, is the...

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Detalles Bibliográficos
Autores principales: Rizk, Victoria T, Walko, Christine M, Brohl, Andrew S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340366/
https://www.ncbi.nlm.nih.gov/pubmed/30697061
http://dx.doi.org/10.2147/PGPM.S170612