Cargando…

Click to enter: activation of oligo-arginine cell-penetrating peptides by bioorthogonal tetrazine ligations

Cell-penetrating peptides are able to transport a wide variety of cargo across cell membranes. Although promising, they are not often considered for therapeutic purposes as they lack controllable activity and cell selectivity. We have developed an activation strategy based on a split octa-arginine c...

Descripción completa

Detalles Bibliográficos
Autores principales: Bode, Saskia A., Timmermans, Suzanne B. P. E., Eising, Selma, van Gemert, Sander P. W., Bonger, Kimberly M., Löwik, Dennis W. P. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340402/
https://www.ncbi.nlm.nih.gov/pubmed/30746105
http://dx.doi.org/10.1039/c8sc04394a