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Primed Track, high-fidelity lineage tracing in mouse pre-implantation embryos using primed conversion of photoconvertible proteins

Accurate lineage reconstruction of mammalian pre-implantation development is essential for inferring the earliest cell fate decisions. Lineage tracing using global fluorescence labeling techniques is complicated by increasing cell density and rapid embryo rotation, which hampers automatic alignment...

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Detalles Bibliográficos
Autores principales: Welling, Maaike, Mohr, Manuel Alexander, Ponti, Aaron, Rullan Sabater, Lluc, Boni, Andrea, Kawamura, Yumiko K, Liberali, Prisca, Peters, Antoine HFM, Pelczar, Pawel, Pantazis, Periklis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340703/
https://www.ncbi.nlm.nih.gov/pubmed/30663981
http://dx.doi.org/10.7554/eLife.44491