Mitochondrial superoxide generation induces a parkinsonian phenotype in zebrafish and huntingtin aggregation in human cells

Superoxide generation by mitochondria respiratory complexes is a major source of reactive oxygen species (ROS) which are capable of initiating redox signaling and oxidative damage. Current understanding of the role of mitochondrial ROS in health and disease has been limited by the lack of experiment...

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Detalles Bibliográficos
Autores principales: Pinho, Brígida R., Reis, Sara D., Hartley, Richard C., Murphy, Michael P., Oliveira, Jorge M.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340810/
https://www.ncbi.nlm.nih.gov/pubmed/30389496
http://dx.doi.org/10.1016/j.freeradbiomed.2018.10.446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340810/
https://www.ncbi.nlm.nih.gov/pubmed/30389496
http://dx.doi.org/10.1016/j.freeradbiomed.2018.10.446

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