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VH1-69 Utilizing Antibodies Are Capable of Mediating Non-neutralizing Fc-Mediated Effector Functions Against the Transmitted/Founder gp120

Multiple antibody effector functions arise in HIV-1 infection that could be harnessed to protect against infection or clear the persistent reservoir. Here, we have investigated the genetic and functional memory B cell and antibody landscape present during early infection in six individuals infected...

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Detalles Bibliográficos
Autores principales: Smith, S. Abigail, Burton, Samantha L., Kilembe, William, Lakhi, Shabir, Karita, Etienne, Price, Matt, Allen, Susan, Derdeyn, Cynthia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341001/
https://www.ncbi.nlm.nih.gov/pubmed/30697215
http://dx.doi.org/10.3389/fimmu.2018.03163