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Streptococcus endopeptidases promote HPV infection in vitro

Both cervical and throat cancers are associated with human papillomavirus (HPV). HPV infection requires cleavage of the minor capsid protein L2 by furin. While furin is present in the vaginal epithelium, it is absent in oral epithelial basal cells where HPV infection occurs. The objective of this st...

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Detalles Bibliográficos
Autores principales: Pavlova, Sylvia I., Wilkening, Reid V., Federle, Michael J., Lu, Yu, Schwartz, Joel, Tao, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341032/
https://www.ncbi.nlm.nih.gov/pubmed/29675996
http://dx.doi.org/10.1002/mbo3.628