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Spatial Principles of Chromatin Architecture Associated With Organ-Specific Gene Regulation

Packaging of the genome in the nucleus is a non-random process that is thought to directly contribute to cell type-specific transcriptomes, although this hypothesis remains untested. Epigenome architecture, as assayed by chromatin conformation capture techniques, such as Hi-C, has recently been desc...

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Detalles Bibliográficos
Autores principales: Chapski, Douglas J., Rosa-Garrido, Manuel, Hua, Nan, Alber, Frank, Vondriska, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341059/
https://www.ncbi.nlm.nih.gov/pubmed/30697540
http://dx.doi.org/10.3389/fcvm.2018.00186